98474-00-1

Upstream product

• 1445-91-6 (S)-1-phenylethanol 
• 95045-21-9 (-)-(P)-1-methoxycarbonyl-5,6,8,10-tetramethylheptalene-2-carboxylic acid 
• 1517-69-7 (R)-1-phenylethanol 
• 115401-13-3 1-benzyloxy-5,6,8,10-tetramethylheptalene-2-carboxylic acid 
• 100-51-6 benzyl alcohol 

Relevant academic research and scientific papers

132. Formation of cyclic "ortho"-Anhydrides of Heptalene-1,2-dicarboxylic Acids

1-(Alkoxycarbonyl)heptalene-2-carboxylic acids as well as 2-(alkoxycarbonyl)heptalene-1-carboxylic acids react with the iminium salt formed from N,N-dimethylformamide (DMF) and oxalyl chloride, in the presence of an alcohol, to yield the corresponding cyc

First Optically Active Heptalenes and their Absolute Configuration

It is shown that dimethyl 7-isopropyl-5,10-dimethylheptalene-1,2-dicarboxylate (1) and dimethyl 5,6,8,10-tetramethylheptalene-1,2-dicarboxylate (2) can be resolved via the corresponding mono-acids and with the aid of optically active primary or secondary amines such as 1-phenylethylamine or ephedrine into the (-)-(P)-and (+)-(M)-enantiomeres, respectively.Charactheristic for the (P)-chirality of the heptalene ?-skeleton with C2 or pseudo-C2 symmetry are two (-)-CE's at the long wavelength region (450-300 nm) followed by at least one intense (+)-CE at wavelengths about or below 300 nm.The absolute configuration of the heptalenes was correlated with the well-established absolute configuration of (+)-(R)- and (-)-(S)-1-phenylethanol.