98502-98-8Relevant academic research and scientific papers
Antilipolytic activity of new pyrazine N-oxides. II.
Cozzi,Pillan,Bertone,et al.
, p. 241 - 245 (2007/10/02)
The synthesis and the pharmacological evaluation of some new pyrazine-N-oxides related to Acipimox, namely the corresponding carbinol and some of its ethers, are described. Some of these compounds show strong antilipolytic activity which was significantly long-lasting in the case of 2-methoxymethyl-5-methylpyrazine-4-oxide. This compound was chosen for further extensive pharmacological evaluation.
