98534-78-2Relevant academic research and scientific papers
SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONISTS
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Page/Page column 158, (2011/02/24)
Disclosed are compounds of Formula (I), or a stereoisomer or a pharmaceutically acceptable salt thereof, wherein: A is formula (II) Q is a substituted 5-membered monocyclic heteroaryl group; W is CH2, O, or NH; and R1, R2, R3, R4, R5, R6, m, n, t, and x are defined herein. Also disclosed are methods of using such compounds as selective agonists for G protein-coupled receptor S1P1, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.
Herbicidal 5-halo-1-halophenyl-1H-pyrazole-4-carbonitriles
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, (2008/06/13)
The present invention is directed to herbicidal compounds of the formula STR1 wherein each R1 independently is halogen; R2 is halo or trifluoromethyl; and n is 1-5; with the provisos that when n is 1, R1 is other than fluorine, and when n is 2 and each R1 is chlorine, at least one R1 is located at a para or ortho position on the phenyl ring.
Herbicidal and algicidal 1,5-disubstituted-1H-pyrazole-4-carboxamides
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, (2008/06/13)
1,5-Disubstituted-1H-pyrazole-4-carboxamide derivatives, useful as herbicides and aquatic algicides.
