98534-83-9

Basic information

• Product Name: 1-(4-METHOXYPHENYL)-5-(TRIFLUOROMETHYL)&
• Synonyms: 1-(4-METHOXYPHENYL)-5-(TRIFLUOROMETHYL)&
• CAS NO: 98534-83-9
• Molecular Formula: C₁₂H₉F₃N₂O₃
• Molecular Weight: 286.208
• Product Categories: Building Blocks;Heterocyclic Building Blocks;Pyrazoles
• Mol File: 98534-83-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 163-167 °C(lit.)
• Boiling Point: 403.1°C at 760 mmHg
• Flash Point: 197.6°C
• Appearance: /
• Density: 1.44g/cm³
• Vapor Pressure: 3.21E-07mmHg at 25°C
• Refractive Index: 1.545
• CAS DataBase Reference: 1-(4-METHOXYPHENYL)-5-(TRIFLUOROMETHYL)&(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-METHOXYPHENYL)-5-(TRIFLUOROMETHYL)&(98534-83-9)
• EPA Substance Registry System: 1-(4-METHOXYPHENYL)-5-(TRIFLUOROMETHYL)&(98534-83-9)

Safety Data

• Hazard Codes: Xi
• Statements: 43
• Safety Statements: 26-36/37
• WGK Germany: 3
• Hazardous Substances Data: 98534-83-9(Hazardous Substances Data)

Usage

General Description

1-(4-Methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylic acid is a chemical compound that belongs to the class of pyrazole derivatives. It is structurally composed of a pyrazole ring with a 4-methoxyphenyl group and a trifluoromethyl group attached at the 1 and 5 positions, respectively. 1-(4-METHOXYPHENYL)-5-(TRIFLUOROMETHYL)& has potential applications in the pharmaceutical industry, particularly in the development of new drugs with diverse pharmacological activities. Its unique chemical structure makes it a promising candidate for further research and development in the field of medicinal chemistry.

InChI:InChI=1/C12H9F3N2O3/c1-20-8-4-2-7(3-5-8)17-10(12(13,14)15)9(6-16-17)11(18)19/h2-6H,1H3,(H,18,19)

Upstream product

• 571-55-1 ethyl 2-(ethoxymethylidene)-4,4,4-trifluoro-3-oxobutanoate 
• 19501-58-7 4-methoxyphenylhydrazine hydrochloride 
• 112055-38-6 ethyl 1-(4-methoxyphenyl)-5-(trifluoromethyl)-1H-pyrazole-4-carboxylate 

Relevant articles and documents

Discovery of Novel Inhibitors of Uridine Diphosphate- N-Acetylenolpyruvylglucosamine Reductase (MurB) from Pseudomonas aeruginosa, an Opportunistic Infectious Agent Causing Death in Cystic Fibrosis Patients

Pseudomonas aeruginosa is of major concern for cystic fibrosis patients where this infection can be fatal. With the emergence of drug-resistant strains, there is an urgent need to develop novel antibiotics against P. aeruginosa. MurB is a promising target

SPHINGOSINE-1-PHOSPHATE RECEPTOR AGONISTS

Disclosed are compounds of Formula (I), or a stereoisomer or a pharmaceutically acceptable salt thereof, wherein: A is formula (II) Q is a substituted 5-membered monocyclic heteroaryl group; W is CH2, O, or NH; and R1, R2, R3, R4, R5, R6, m, n, t, and x are defined herein. Also disclosed are methods of using such compounds as selective agonists for G protein-coupled receptor S1P1, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating, preventing, or slowing the progression of diseases or disorders in a variety of therapeutic areas, such as autoimmune diseases and vascular disease.