98549-88-3 Usage
Chemical Properties
Light yellow solid
Uses
1H-?Pyrrolo[2,?3-?b]?pyridin-?5-?ol is a reagent used in the synthesis of potent VEGFR-2 inhibitors. 7-Azaindole derivative identified as an intermediate in the synthesis of Venetoclax (A112430), a potent and selective BCL-2 inhibitor that achieves potent antitumour activity while sparing platelets.
Check Digit Verification of cas no
The CAS Registry Mumber 98549-88-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,8,5,4 and 9 respectively; the second part has 2 digits, 8 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 98549-88:
(7*9)+(6*8)+(5*5)+(4*4)+(3*9)+(2*8)+(1*8)=203
203 % 10 = 3
So 98549-88-3 is a valid CAS Registry Number.
InChI:InChI=1/C7H6N2O/c10-6-3-5-1-2-8-7(5)9-4-6/h1-4,10H,(H,8,9)
98549-88-3Relevant articles and documents
Synthesis of functionalized 7-azaindoles via directed ortho-metalations
L'Heureux, Alexandre,Thibault, Carl,Ruel, Réjean
, p. 2317 - 2319 (2007/10/03)
Functionalization at C-5 of 4-fluoro- and 4-chloro-1-triisopropylsilyl-7- azaindole, 1 and 2, respectively, leads to a variety of new substituted 7-azaindole derivatives. We also describe two approaches to introduce functionality at C-6.
