98555-09-0

Upstream product

• 2458-12-0 3-amino-p-toluic acid 

Downstream Products

• 1038343-37-1 ethyl 1-(2-methyl-5-carboxyphenyl)-[1,2,3]triazole-4-carboxylate 
• 1334682-61-9 N-(5-tert-butyl-1,2-oxazol-3-yl)-3-[4-[5-[2-dimethylaminoethyl(methyl)amino]pyridin-3-yl]triazol-1-yl]-4-methylbenzamide 
• 1334685-39-0 C₂₂H₂₁BrN₆O₂ 
• 1334682-59-5 N-(4-tert-butylpyridin-2-yl)-4-methyl-3-[4-[5-(4-methylpiperazin-1-yl)pyridin-3-yl]triazol-1-yl]benzamide 
• 1334682-56-2 N-(5-tert-butyl-1,2-oxazol-3-yl)-4-methyl-3-[4-[5-(4-methylpiperazin-1-yl)pyridin-3-yl]triazol-1-yl]benzamide 
• 1001203-00-4 C₁₅H₁₇N₅O₂ 
• 1096697-97-0 4-methyl-3-(4-pyridin-3-yl-[1,2,3]triazol-1-yl)-benzoic acid 
• 1096697-98-1 C₁₉H₁₉N₅O₃ 
• 1001202-99-8 C₁₅H₁₅N₅O₂ 
• 865798-05-6 3-[4-(6-chloro-pyridin-3-yl)-1,2,3-triazol-1-yl]-4-methyl-benzoic acid 
• 865798-11-4 4-methyl-3-[4-(6-morpholin-4-ylmethyl-pyridin-3-yl)-1,2,3-triazol-1-yl]-benzoic acid 
• 865798-12-5 4-methyl-3-[5-(6-morpholin-4-ylmethyl-pyridin-3-yl)-1,2,3-triazol-1-yl]-benzoic acid 
• 865798-09-0 3-{4-[6-(cyclopropylmethyl-amino)-pyridin-3-yl]-1,2,3-triazol-1-yl}-4-methyl-benzoic acid 
• 695178-91-7 1-(5-carboxy-2-methyl-phenyl)-1H-1,2,3-triazole-4-carboxylic acid methyl ester 

Relevant academic research and scientific papers

Synthesis and Antimicrobial Activity of Novel Bis-1,2,3-triazol-1H-4-yl-substituted Aryl Benzimidazole-2-thiol Derivatives

Abstract: Novel bis-1,2,3-triazol-1H-4-yl-substitutedaryl benzimidazole-2-thiol derivatives have been synthesized from 5-methoxy and5-difluoromethoxy bis-propargyl substituted benzimidazole-2-thiols using the“click chemistry,” tested for their antimicrobi

B-RAF KINASE INHIBITORS

The present invention encompasses compounds of general formula (1) where in the groups R0to R3 and L are defined as in claim 1, which are suitable for the 5 treatment of diseases characterised by excessive or abnormal cell proliferat

NEW CHEMICAL COMPOUNDS

The present invention encompasses compounds of general formula (1), wherein the groups R1 to R3 and L are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and their use for

Structure-based design and subsequent optimization of 2-tolyl-(1,2,3-triazol-1-yl-4-carboxamide) inhibitors of p38 MAP kinase

A computer-aided drug design strategy leads to the identification of a new class of p38 inhibitors based on the 2-tolyl-(1,2,3-triazol-1-yl-4-carboxamide) scaffold. The tolyl triazole amides provided a potent platform amenable to optimization. Further exp

NEW CHEMICAL COMPOUNDS

The present invention encompasses compounds of general formula (1) wherein the groups R2 to R4, L, Q and n are defined as in claim 1, which are suitable for the treatment of diseases characterised by excessive or abnormal cell proliferation, and the use thereof for preparing a medicament having the above-mentioned properties.

Cytokine inhibitors

Disclosed are compounds of formula (I) Where Ar1, X, R3, R4, R5 and R6 are defined herein. The compounds of the invention inhibit production of cytokines involved in inflammatory processes and are thu