98588-80-8

Upstream product

• 106-96-7 propargyl bromide 
• 95-76-1 m,p-dichloroaniline 

Downstream Products

• 101081-76-9 N,N'-bis-(3,4-dichloro-phenyl)-N-prop-2-ynyl-urea 
• 31894-28-7 N-{2,2,2-Trichloro-1-[(3,4-dichloro-phenyl)-prop-2-ynyl-amino]-ethyl}-acetamide 
• 31896-06-7 N-{2,2,2-Trichloro-1-[(3,4-dichloro-phenyl)-prop-2-ynyl-amino]-ethyl}-benzamide 
• 31893-82-0 N-{2,2,2-Trichloro-1-[(3,4-dichloro-phenyl)-prop-2-ynyl-amino]-ethyl}-acrylamide 
• 123685-31-4 2-amino-6-[[(3,4-dichlorophenyl)-2-propynylamino]methyl]-4(3H)-quinazolinone 
• 123685-29-0 6-[[(3,4-dichlorophenyl)-2-propynylamino]methyl]-4(3H)-quinazolinone 
• 123685-40-5 2,2-dimethylpropanoic acid, [6-[[(3,4-dichlorophenyl)-2-propynylamino]methyl]-4-oxo-3(4H)-quinazolinyl]methyl ester 
• 123685-46-1 N-<6-<<(3,4-dichlorophenyl)-2-propynylamino>methyl>-3,4-dihydro-4-oxo-2-quinazolinyl>-2,2-dimethylpropanamide 
• 31893-67-1 2,2-Dimethyl-N-{2,2,2-trichloro-1-[(3,4-dichloro-phenyl)-prop-2-ynyl-amino]-ethyl}-propionamide 
• 31893-48-8 2-Chloro-N-{2,2,2-trichloro-1-[(3,4-dichloro-phenyl)-prop-2-ynyl-amino]-ethyl}-acetamide 

Relevant academic research and scientific papers

Potent inhibition of thymidylate synthase by two series of nonclassical quinazolines

The synthesis and biological activity of two series of nonclassical thymidylate synthase (TS) inhibitors are described. The first is a series of 10-propargyl-5.8-dideazafolic acid derivatives (10a-j) and the second is a series of the analogous 2-desamino