98591-08-3Relevant academic research and scientific papers
Gold-catalyzed N, O-functionalizations of 6-allenyl-1-ynes with n-hydroxyanilines to construct benzo[b]-azepin-4-one cores
Raj, Antony Sekar Kulandai,Kale, Balaji S.,Mokar, Bhanudas Dattatray,Liu, Rai-Shung
supporting information, p. 5340 - 5343 (2017/11/07)
Gold-catalyzed reactions of 6-allen-1-ynes with N-hydroxyanilines afford thermally stable benzoazepin-4-ones in anti-selectivity; these anti-configured products are easily isomerized to their syn-isomers on a silica column. The mechanism of reactions likely involve initial nitrone/allene cycloadditions, followed by skeletal rearrangement of resulting intermediates.
