PARATHYROID HORMONE (1-34), RAT is a synthetic fragment of the parathyroid hormone (PTH) that consists of the first 34 amino acids of the rat parathyroid hormone. It is a peptide hormone that plays a crucial role in regulating calcium and phosphate metabolism in the body. This fragment has been widely used in research to study the effects of PTH on various physiological processes.
98614-76-7
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Basic information
- Product Name: PARATHYROID HORMONE (1-34), RAT
- Synonyms: pTH (1-34) (rat)|PARATHYROID HORMONE (1-34),RAT;PTH (1-34) (RAT);PARATHYROID HORMONE RAT: FRAGMENT 1-34;PARATHYROID HORMONE (1-34), RAT;RPTH 1-34;ALA-VAL-SER-GLU-ILE-GLN-LEU-MET-HIS-ASN-LEU-GLY-LYS-HIS-LEU-ALA-SER-VAL-GLU-ARG-MET-GLN-TRP-LEU-ARG-LYS-LYS-LEU-GLN-ASP-VAL-HIS-ASN-PHE;ALA-VAL-SER-GLU-ILE-GLN-LEU-MET-HIS-ASN-LEU-GLY-LYS-HIS-LEU-ALA-SER-VAL-GLU-ARG-MET-GLN-TRP-LEU-ARG-LYS-LYS-LEU-GLN-ASP-VAL-HIS-ASN-PHE RAT;H-ALA-VAL-SER-GLU-ILE-GLN-LEU-MET-HIS-ASN-LEU-GLY-LYS-HIS-LEU-ALA-SER-VAL-GLU-ARG-MET-GLN-TRP-LEU-ARG-LYS-LYS-LEU-GLN-ASP-VAL-HIS-ASN-PHE-OH
- CAS NO:98614-76-7
- Molecular Formula: C180H291N55O48S2
- Molecular Weight: 4057.70624
- EINECS: N/A
- Product Categories: peptide;Parathyroid Hormone (PTH)Peptides and Proteins;Parathyroid Hormone Fragments;Hormones;Other Protein/Peptide Hormones;Peptides for Cell Biology
- Mol File: 98614-76-7.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /powder
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: −20°C
- Solubility: N/A
- Water Solubility: Soluble in water or 0.1% acetic acid.
- CAS DataBase Reference: PARATHYROID HORMONE (1-34), RAT(CAS DataBase Reference)
- NIST Chemistry Reference: PARATHYROID HORMONE (1-34), RAT(98614-76-7)
- EPA Substance Registry System: PARATHYROID HORMONE (1-34), RAT(98614-76-7)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany: 3
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 98614-76-7(Hazardous Substances Data)
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98614-76-7 Usage
Uses
Used in Pharmaceutical Research:PARATHYROID HORMONE (1-34), RAT is used as a research tool for studying the in vivo effect of parathyroid hormone on the intestinal HCO3-secretion in rats. This helps researchers understand the role of PTH in calcium and phosphate homeostasis and its potential therapeutic applications.
Used in Hypertension Research:
PARATHYROID HORMONE (1-34), RAT is used as an experimental agent for investigating its effect on high-phosphate diet-induced elevation of blood pressure in rats. This research can provide insights into the relationship between PTH levels, phosphate metabolism, and blood pressure regulation, potentially leading to the development of new treatments for hypertension.
Used in Osteoporosis Research:
PARATHYROID HORMONE (1-34), RAT is used as a therapeutic agent in the study of its potential to increase bone density and improve bone strength in osteoporosis. By mimicking the actions of the native parathyroid hormone, this fragment may help in the development of new treatments for osteoporosis and other bone-related disorders.
Used in Calcium and Phosphate Metabolism Studies:
PARATHYROID HORMONE (1-34), RAT is used as a biological probe to investigate the mechanisms underlying calcium and phosphate regulation in the body. This research can contribute to a better understanding of the role of PTH in maintaining mineral homeostasis and identifying potential targets for therapeutic intervention in related disorders.
Biochem/physiol Actions
Parathyroid Hormone Fragment 1-34 is a parathyroid hormone (PTH) analog. It is implicated in the stimulation of intracellular cAMP accumulation and it induces osteocalcin (OC) promoter activity.Check Digit Verification of cas no
The CAS Registry Mumber 98614-76-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,8,6,1 and 4 respectively; the second part has 2 digits, 7 and 6 respectively.Calculate Digit Verification of CAS Registry Number 98614-76:
(7*9)+(6*8)+(5*6)+(4*1)+(3*4)+(2*7)+(1*6)=177
177 % 10 = 7
So 98614-76-7 is a valid CAS Registry Number.
98614-76-7Upstream product
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PARATHYROID HORMONE (1-34), RAT
