98625-26-4 Usage
Description
S(-)-BAY K 8644, also known as (S)-(-)-Bay K8644, is a chemical compound that acts as a potent L-type calcium channel (LTCC) agonist. It is primarily used in scientific research and has been found to have various applications in different fields.
Uses
Used in Neuroscience Research:
S(-)-BAY K 8644 is used as a LTCC agonist in the suprachiasmatic nucleus (SCN) slices for studying the effects of L-type calcium channels on neuronal activity and function.
Used in Cardiology Research:
S(-)-BAY K 8644 is used as a LTCC agonist to induce arrhythmia in rats, which helps researchers understand the role of L-type calcium channels in cardiac function and the development of arrhythmias.
Biological Activity
L-type Ca 2+ -channel activator with positive inotropic, vasoconstrictive and behavioral effects in vivo . Enantiomer of (1,4-Dihydro-2,6-dimethyl-5-nitro-4-[2-(trifluoromethyl)phenyl]-3-pyridinecarboxylic acid, methyl ester ).
Biochem/physiol Actions
(S)-(-)-Bay K8644 enhances Ca2+ current, whereas the (+)-Bay K 8644 is a weak Ca2+ channel antagonist. Bay K 8644 is lipophilic and it effectively scavenges superoxide anions.
Check Digit Verification of cas no
The CAS Registry Mumber 98625-26-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,8,6,2 and 5 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 98625-26:
(7*9)+(6*8)+(5*6)+(4*2)+(3*5)+(2*2)+(1*6)=174
174 % 10 = 4
So 98625-26-4 is a valid CAS Registry Number.
InChI:InChI=1/C16H15F3N2O4/c1-8-12(15(22)25-3)13(14(21(23)24)9(2)20-8)10-6-4-5-7-11(10)16(17,18)19/h4-7,13,20H,1-3H3/t13-/m0/s1
