98626-87-0

Basic information

• Product Name: (4-Chloro-phenyl)-(4-phenyl-thiazol-2-yl)-amine; hydrobromide
• Synonyms: (4-Chloro-phenyl)-(4-phenyl-thiazol-2-yl)-amine; hydrobromide
• CAS NO: 98626-87-0
• Molecular Weight: 367.697
• Mol File: 98626-87-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (4-Chloro-phenyl)-(4-phenyl-thiazol-2-yl)-amine; hydrobromide(CAS DataBase Reference)
• NIST Chemistry Reference: (4-Chloro-phenyl)-(4-phenyl-thiazol-2-yl)-amine; hydrobromide(98626-87-0)
• EPA Substance Registry System: (4-Chloro-phenyl)-(4-phenyl-thiazol-2-yl)-amine; hydrobromide(98626-87-0)

Safety Data

• Hazardous Substances Data: 98626-87-0(Hazardous Substances Data)

Upstream product

• 2131-55-7 4-Chlorophenyl isothiocyanate 
• 70-11-1 α-bromoacetophenone 
• 3696-23-9 N-(4-chlorophenyl)thiourea 
• 4651-78-9 2-bromo-1-phenylethylidenemalononitrile 
• 103061-75-2 2-[2-(4-Chloro-phenylamino)-4-phenyl-4,5-dihydro-thiazol-4-yl]-malononitrile; hydrobromide 

Relevant articles and documents

Convenient one-pot formation of highly functionalized 5-bromo-2-aminothiazoles, potential endocannabinoid hydrolase MAGL inhibitors

Highly functionalized 5-bromo-2-amino-1,3-thiazoles bearing various substituents could be easily prepared by a rapid and efficient one-pot method, using simple starting materials and mild conditions while avoiding the use of metal catalysts or inconvenient reagents such as elemental halogens. These useful products can serve as starting materials for other reactions or as pharmacologically interesting compounds. In our work we have shown that the resulting 5-bromothiazole compounds could lead to monoacylglycerol lipase (MAGL) inhibition in the μM range.

2-ARYLIMINO-3-THIAZOLINES - FORMATION OF UNUSUAL TAUTOMERS OF 2-ARYLAMINO-THIAZOLINES - A REVISION

In contrast to previously reported results the products formed in the reaction of arylthioureas with 3-bromomethyl-2-cyanocinnamonitrile are not 2-arylimino-3-thiazolines but 2-arylamino-4-dicyanomethyl-2-thiazolines.