98629-44-8 Usage
General Description
15-deoxymethylspergualin is a synthetic derivative of the naturally occurring compound spergualin. It is used in medical research and has shown potential as an immunosuppressant medication. 15-deoxymethylspergualin inhibits the growth of T cells, which are a type of white blood cell involved in the immune response. This property makes it useful in preventing rejection of transplanted organs and in treating autoimmune disorders. Additionally, it has shown promise in the treatment of certain types of cancer. Research on the potential uses and mechanisms of action of 15-deoxymethylspergualin is ongoing, and it may have future applications in the field of medicine.
Check Digit Verification of cas no
The CAS Registry Mumber 98629-44-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,8,6,2 and 9 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 98629-44:
(7*9)+(6*8)+(5*6)+(4*2)+(3*9)+(2*4)+(1*4)=188
188 % 10 = 8
So 98629-44-8 is a valid CAS Registry Number.
InChI:InChI=1/C18H39N7O3/c1-28-17(16(27)23-13-7-6-11-22-12-8-10-19)25-15(26)9-4-2-3-5-14-24-18(20)21/h17,22H,2-14,19H2,1H3,(H,23,27)(H,25,26)(H4,20,21,24)
98629-44-8Relevant articles and documents
Improved synthesis of 15-deoxyspergualin analogs using the Ugi multi-component reaction
Evans, Christopher G.,Smith, Matthew C.,Carolan, James P.,Gestwicki, Jason E.
, p. 2587 - 2590 (2011/06/20)
Spergualin is a natural product that exhibits immunosuppressive, anti-tumor and anti-bacterial activities. Its derivatives, such as 15-deoxyspergualin (15-DSG), have been clinically approved for acute allograft rejection. However, the reported syntheses a