98647-12-2Relevant academic research and scientific papers
Palladium catalyzed addition of arylboronic acid or indole to nitriles: Synthesis of aryl ketones
Das, Tuluma,Chakraborty, Amarnath,Sarkar, Amitabha
supporting information, p. 7198 - 7202 (2015/01/09)
Aryl ketones can be synthesized conveniently by a palladium catalyzed addition of arylboronic acid to nitriles in aqueous triflic acid. This catalytic system was extended to the addition of unprotected indoles to nitriles under a slightly modified condition to produce 3-acyl indoles in good yields.
COMPOUNDS AND METHODS FOR TREATING PROTEIN FOLDING DISORDERS
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Page/Page column 95, (2008/12/05)
The invention is directed to compounds and methods for treating protein folder disorders. In certain embodiments the invention provides compounds and methods for treating neurodegenerative diseases such as Alzheimer's disease, tauopathy, cerebral amyloid angiopathy, Lewy body disease, dementia, Huntington's disease and prion-based spongiform encelopathy. The invention further provides compounds, methods and pharmaceutical compositions for inhibiting tau protein, Aβ protein or α-synuclein protein aggregation.
Acylindole derivatives and their use in pharmaceutical compositions
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, (2008/06/13)
The present invention is concerned with novel acylindole derivatives of the formula (I) and platelet-aggregation inhibiting agents containing them as an active ingredient. STR1 In the formula (I), either R1 and R2 is hydrogen, an alk
