98662-08-9

Upstream product

• 98662-07-8 2-benzoyl-1-(4-cyanobenzyl)-1,2-dihydroisoquinoline-1-carbonitrile 
• 119-65-3 isoquinoline 
• 104-85-8 para-methylbenzonitrile 
• 17201-43-3 4-cyanobenzyl bromide 
• 844-25-7 2-benzoyl-1-cyano-1,2-dihydroisoquinoline 

Downstream Products

• 98662-10-3 1-(4-Carboxy)-benzylisochinolin 
• 98237-18-4 methyl 4-(isoquinolin-1-ylmethyl)benzoate 
• 98237-28-6 1-(4-Carboxymethylbenzyl)-5,6,7,8-tetrahydroisochinolin 

Relevant academic research and scientific papers

Organocatalytic asymmetric destruction of 1-benzylated Reissert compounds catalysed by quaternary cinchona alkaloids

The enantiomeric enrichment of racemic 1-benzylated Reissert compounds under organocatalytic biphasic conditions is presented. The enrichment is the consequence of an asymmetric destruction of the racemic compounds resulting in the formation of the corres

Oxidant-Triggered C1-Benzylation of Isoquinoline by Iodine-Catalyzed Cross-Dehydrogenative-Coupling with Methylarenes

A practical iodine-catalyzed oxidative functionalization of isoquinolines with methylarenes is developed, which can be triggered by the selected oxidants to produce C1- or N-benzyl-substituted products selectively. This method utilizes readily available isoquinolines and methylarenes as starting materials and proceeds under metal-free conditions with broad substrate scope with respect to methylarenes, avoiding the usage of expensive metal catalysts and generation of halide and metal wastes.