98664-90-5

Upstream product

• 98665-00-0 (E)-2-(Formyl-methoxymethyl-amino)-3-[4-[2-(2-methyl-[1,3]dioxolan-2-yl)-ethyl]-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-acrylic acid ethyl ester 
• 98664-86-9 (S)-Benzyloxycarbonylamino-[(3R,4S)-4-isopropenyl-1-(toluene-4-sulfonyl)-1,3,4,5-tetrahydro-benzo[cd]indol-3-yl]-acetic acid ethyl ester 
• 98665-01-1 (Z)-2-(Formyl-methoxymethyl-amino)-3-[4-[2-(2-methyl-[1,3]dioxolan-2-yl)-ethyl]-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-acrylic acid ethyl ester 
• 98664-87-0 (R)-[(3S,4R)-4-Acetyl-1-(toluene-4-sulfonyl)-1,3,4,5-tetrahydro-benzo[cd]indol-3-yl]-(formyl-methoxymethyl-amino)-acetic acid ethyl ester 
• 98664-88-1 (S)-(Formyl-methoxymethyl-amino)-[(3S,4R)-4-isopropenyl-1-(toluene-4-sulfonyl)-1,3,4,5-tetrahydro-benzo[cd]indol-3-yl]-acetic acid ethyl ester 
• 98664-88-1 (R)-(Formyl-methoxymethyl-amino)-[(3S,4R)-4-isopropenyl-1-(toluene-4-sulfonyl)-1,3,4,5-tetrahydro-benzo[cd]indol-3-yl]-acetic acid ethyl ester 
• 98665-04-4 (Z)-2-Formylamino-3-[4-[2-(2-methyl-[1,3]dioxolan-2-yl)-ethyl]-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-acrylic acid ethyl ester 
• 98664-99-4 (E)-2-Formylamino-3-[4-[2-(2-methyl-[1,3]dioxolan-2-yl)-ethyl]-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-acrylic acid ethyl ester 
• 98665-02-2 (E)-2-(Formyl-methoxymethyl-amino)-3-[4-(3-oxo-butyl)-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-acrylic acid ethyl ester 
• 98665-03-3 (Z)-2-(Formyl-methoxymethyl-amino)-3-[4-(3-oxo-butyl)-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-acrylic acid ethyl ester 
• 98664-85-8 (S)-Amino-[(3R,4S)-4-isopropenyl-1-(toluene-4-sulfonyl)-1,3,4,5-tetrahydro-benzo[cd]indol-3-yl]-acetic acid ethyl ester 
• 98664-93-8 C₃₉H₃₈N₂O₆SSe 
• 98-59-9 p-toluenesulfonyl chloride 
• 71516-34-2 2-((E)-2-Dimethylamino-vinyl)-3-nitro-benzoic acid ethyl ester 

Relevant academic research and scientific papers

A total synthesis of (±)-α-cyclopiazonic acid using a cationic cascade as a key step

The indole alkaloid α-cyclopiazonic acid 1 has been synthesised by a route, which features at its core an acid-catalysed cationic cascade cyclisation terminated by a sulfonamide group.

TOTAL SYNTHESIS OF (+/-)-α-CYCLOPIAZONIC ACID

(+/-)-α-Cyclopiazonic acid (2) was synthesized from 1-methoxycarbonyl-4-(3-oxo-1-butyl)indole (1) by way of 17, 18, and 19 using a reaction of MeLi with a pyrroline derivative 33 in the presence of BF3*Et2O.