Transforming Growth Factor-Beta1 (TGF-β1), human, is a multifunctional cytokine that plays a pivotal role in regulating cell growth, differentiation, and immune responses. It is involved in a wide range of biological processes, such as tissue repair, embryonic development, and immune regulation. TGF-β1 is produced by various cell types and exerts its effects by binding to specific cell surface receptors, activating downstream signaling pathways. Its dysregulation has been associated with numerous diseases, including cancer, fibrosis, and autoimmune disorders, making it a significant target for therapeutic intervention in these conditions.
98726-64-8
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Basic information
- Product Name: TRANSFORMING GROWTH FACTOR-BETA1, HUMAN
- Synonyms: TRANSFORMING GROWTH FACTOR-BETA1 PORCINE;TRANSFORMING GROWTH FACTOR, BETA-1, PORCINE PLATELETS;TRANSFORMING GROWTH FACTOR-BETA1 RECEPTOR II SOLUBLE FRAGMENT, HUMAN;TRANSFORMING GROWTH FACTOR-B1;TRANSFORMING GROWTH FACTOR-BETA1;TRANSFORMING GROWTH FACTOR-BETA1, HUMAN;TRANSFORMING GROWTH FACTOR-BETA1, HUMAN PLATELETS;TRANSFORMING GROWTH FACTOR-BETA1, HUMAN, RECOMBINANT
- CAS NO:98726-64-8
- Molecular Formula:
- Molecular Weight: 0
- EINECS: N/A
- Product Categories: cytokine
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Chemical Properties
- Melting Point: N/A
- Boiling Point: N/A
- Flash Point: N/A
- Appearance: /powder
- Density: N/A
- Refractive Index: N/A
- Storage Temp.: −20°C
- Solubility: N/A
- CAS DataBase Reference: TRANSFORMING GROWTH FACTOR-BETA1, HUMAN(CAS DataBase Reference)
- NIST Chemistry Reference: TRANSFORMING GROWTH FACTOR-BETA1, HUMAN(98726-64-8)
- EPA Substance Registry System: TRANSFORMING GROWTH FACTOR-BETA1, HUMAN(98726-64-8)
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Safety Data
- Hazard Codes: B
- Statements: N/A
- Safety Statements: N/A
- WGK Germany: 3
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 98726-64-8(Hazardous Substances Data)
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98726-64-8 Usage
Uses
Used in Pharmaceutical Industry:TGF-β1, human, is used as a therapeutic target for the treatment of various diseases caused by its dysregulation. The modulation of TGF-β1 signaling is a subject of ongoing research for conditions such as cancer, fibrosis, and autoimmune disorders.
Used in Research Applications:
TGF-β1, human, is used as a research tool in laboratories to study its role in cell growth, differentiation, and immune responses. It aids in understanding the molecular mechanisms underlying its involvement in various biological processes and disease pathogenesis.
Used in Drug Development:
TGF-β1, human, is used in the development of drugs that target its signaling pathways. These drugs aim to modulate TGF-β1 activity to treat diseases associated with its dysregulation, such as cancer, fibrosis, and autoimmune disorders.
Used in Tissue Engineering and Regenerative Medicine:
TGF-β1, human, is used as a growth factor in tissue engineering and regenerative medicine applications. It promotes tissue repair and regeneration by stimulating cell proliferation, differentiation, and extracellular matrix production.
Used in Diagnostic Applications:
TGF-β1, human, can be used as a biomarker in diagnostic tests to assess the presence or severity of diseases associated with its dysregulation. Measuring TGF-β1 levels in biological samples can help in the diagnosis and monitoring of conditions such as cancer, fibrosis, and autoimmune disorders.
Check Digit Verification of cas no
The CAS Registry Mumber 98726-64-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,8,7,2 and 6 respectively; the second part has 2 digits, 6 and 4 respectively.Calculate Digit Verification of CAS Registry Number 98726-64:
(7*9)+(6*8)+(5*7)+(4*2)+(3*6)+(2*6)+(1*4)=188
188 % 10 = 8
So 98726-64-8 is a valid CAS Registry Number.
98726-64-8Upstream product
98726-64-8Downstream Products
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TRANSFORMING GROWTH FACTOR-BETA1, HUMAN
