98736-13-1Relevant academic research and scientific papers
Oxocyclopentenol Syntheses
Wenkert, Ernest,Greenberg, Richard S.,Raju, Muppala S.
, p. 4681 - 4685 (1985)
Metal-assisted decomposition of α-diazo carbonyl compounds in 1,2-dialkoxy-1-alkenes are shown to yield β,β'-dialkoxycyclopropyl carbonyl systems, whose acid hydrolysis produces α-alkoxy-γ-dicarbonyl substances.Intramolecular condensations of the latter lead to oxocyclopentenols.Application of this reaction scheme to the syntheses of a prostaglandin intermediate and of tetrahydropyrethrolone is described.
