98751-34-9Relevant academic research and scientific papers
Direct synthesis of nitroaryl acetylenes from acetylenes and nitroarenes: Via oxidative nucleophilic substitution of hydrogen
Bujok, Robert,Makosza, Mieczys?aw
, p. 12650 - 12652 (2016/10/31)
Acetylenic carbanions add to nitroarenes (dinitrobenzenes, nitropyridines, etc.) to form σH-adducts that are subsequently oxidized by DDQ according to the oxidative nucleophilic substitution of hydrogen (ONSH) pathway to give nitroaryl acetylen
Chemistry of aminophenols. Part 2: A general and efficient synthesis of indoles possessing a nitrogen substituent at the C4, C5, C6, and C7 positions
Dai, Wei-Min,Sun, Li-Ping,Guo, Dian-Shun
, p. 7699 - 7702 (2007/10/03)
A general and efficient synthesis of indoles possessing a nitrogen substituent at the C4, C5, C6, and C7 positions has been developed. Starting from commercially available nitro 2-aminophenols, 5-, 6-, and 7-arenesulfamoylindoles were synthesized via a ba
Arylation with 1,3-Dinitroarenes and Copper(I) t-Butoxide. Scope and Limitations
Carter, Stephen D.,Wallace, Timothy W.
, p. 1601 - 1633 (2007/10/02)
The reaction of 1,3-dinitrobenzene with copper(I) t-butoxide and an iodoarene, which produces a 2,6-dinitrobiphenyl, has been stidied in detail with a variety of substrates.Iodoarenes containing ester, aldehyde, or other halogen functions were effective, but replacement of the iodoarene with a bromoarene, iodoalkyne, or iodoalkene resulted in less efficient coupling, promoting side-reactions.On replacing the second nitro group on the dinitrobenezene with nitrile, ester, amide, or trifluoromethyl groups, little or no coupling was observed.Limiting side-reactions usually involved the decomposition of substrates by t-butoxide via nucleophilic substitution, elimination, or deprotonation.A mechanism based on reversible cupration of the dinitroarene is proposed.
