98752-29-5Relevant academic research and scientific papers
Ecofriendly synthesis of halogenated flavonoids and evaluation of their antifungal activity
Bernini, Roberta,Pasqualetti, Marcella,Provenzano, Gianfranco,Tempesta, Sabrina
, p. 2980 - 2987 (2015/04/22)
Brominated and chlorinated flavonoids belonging to different classes (flavanones, flavones and catechins) were prepared from the corresponding flavonoids by a simple and ecofriendly procedure based on the use of sodium halides, aqueous hydrogen peroxide and acetic acid. Pure samples of substrates and products were tested against Trichoderma koningii, Fusarium oxysporum and Cladosporium cladosporioides, common saprotrophic soil and seed fungi, potential pathogens for humans and their activity was expressed as linear mycelial growth inhibition (%). Among them, 8-chloro-5,7,3′,4′-tetramethoxyepicatechin 29, a novel catechin derivative, exhibited a remarkable effect against all tested fungi also at low concentrations.
Selective halogenation of flavanones
Bovicelli, Paolo,Bernini, Roberta,Antonioletti, Roberto,Mincione, Enrico
, p. 5563 - 5567 (2007/10/03)
A mild, efficient and regioselective method for the selective halogenation of flavonoids is presented. Halogenated flavanones and flavones are considered potential benzodiazepine receptor ligands and with DMD/NaX or oxone/acetone/water/NaX systems they can be synthesised in preparative amounts.
A SPECIES REACTIVE WITH NITRATE ORGANIC SUBSTRATES IS GENERATED BY ANODIC OXIDATION OF PERCHLORATES IN ACETONITRILE
Murase, Masayuki,Kotani, Eiichi,Ide, Rika,Fukuoka, Masamichi,Tobinaga, Seisho
, p. 1607 - 1610 (2007/10/02)
The reaction of a solution obtained by anodic oxidation of tetraethylammonium perchlorate in MeCN with 5,7,4'-trimetoxyflavanone or 7-methoxycoumarin afforded a chlorinated derivative 1 and the nitrated derivatives 2, 3, and 4, or 6-nitro-7-methoxycoumarin. - KEYWORDS - anodic oxidation; tetraethylammonium perchlorate; acetonitrile; flavanone; coumarin; nitration
