98769-47-2

Upstream product

• 107-59-5 tert-Butyl chloroacetate 
• 655-48-1 DL-1,2-diphenylethane-1,2-diol 

Downstream Products

• 80158-27-6 (+/-)-2,2'-(1,2-diphenyl-1,2-ethanedioxy)-diethanol 
• 72638-74-5 2R^*,3R^*,11R^*,12S^*-2,3,11,12-tetraphenyl<18>crown-6 
• 98769-50-7 2R^*,3R^*,11R^*,12S^*-11,12-dideutero-2,3,11,12-tetraphenyl<18>crown-6 

Relevant academic research and scientific papers

SYNTHESIS OF (-)-2S,3S,11S,12R-2,3,11,12-TETRAPHENYLCROWN-6

The synthesis of (-) 2S,3S,11S,12R-2,3,11,12-tetraphenyl-crown-6 from (-)-1S,2S-hydrobenzoin and meso-hydrobenzoin is described.Chemical shifts and vicinal coupling constants of the benzylic protons in the 2S,3S and 11S,12R substructures in the free ligands and in complexes with KSCN and 1-phenylethylammonium bromides and a brief discussion of the related conformational changes are also presented.A detailed procedure for the resolution of racemic hydrobenzoin is given.