98786-26-6Relevant academic research and scientific papers
Synthesis method of 1,1'-(hexa-2,4-diyne-1,6-diyl)bis(3-alkyl urea) compound
-
Paragraph 0042; 0051-0056, (2020/07/03)
The invention relates to a synthesis method of a 1,1'-(hexa-2,4-diyne-1,6-diyl)bis(3-alkyl urea) compound. The synthesis method comprises the following steps: (1) reacting a compound represented by formula I with ammonium hydroxide in the presence of a solvent to obtain a compound represented by formula II; and (2) reacting the compound of formula II with a compound represented by formula III in the presence of a solvent to prepare the 1,1'-(hexa-2,4-diyne-1,6-diyl)bis(3-alkyl urea) compound represented by formula IV, wherein the structural formula of the compound of formula I is shown in thespecification, the structural formula of the compound of formula II is shown in the specification, the structural formula of the compound of formula III is shown in the specification, the structural formula of the compound of formula IV is shown in the specification, and R in the formulas is a C1-C10 alkyl group. The synthesis method disclosed by the invention is simple in reaction operation and easy in reaction control, does not need cuprous chloride or oxygen, does not need hydrochloric acid to terminate the reaction, and is simpler, more convenient and higher in yield compared with the existing published synthesis method.
Particle size control for acetylenic agents useful in condition monitoring systems
-
Page/Page column 16, (2008/06/13)
Precipitation of polyacetylenic agents can be effected with control of a particle size parameter such as mean size or spread, by mixing a warm solution of the acetylenic agent with a cold precipitation fluid and appropriate selection of a constituent of the cold precipitation fluid and/or of the temperature conditions and collecting the precipitated acetylenic agent. Precipitation additives such as nitrocellulose or gelatin can usefully be employed. Solvents such as aqueous methanol and ethyl 3-ethoxypropionate can be useful. Polyacetylenic agents, e.g. substituted diacetylenics are useful to provide visual changes in condition-monitoring indicators such as time-temperature indicators, “TTIs”, useful as freshness indicators for radiation exposure monitoring and for other purposes. Controlled, small and/or consistent particle sizes of such polyacetylenic agents are helpful in providing consistent commercial properties, especially in inks in which they may be formulated.
