98836-82-9Relevant academic research and scientific papers
Amination of heteroaryl chlorides: Palladium catalysis or SNAr in green solvents?
Walsh, Katie,Sneddon, Helen F.,Moody, Christopher J.
, p. 1455 - 1460 (2013)
The reaction of heteroaryl chlorides in the pyrimidine, pyrazine and quinazoline series with amines in water in the presence of KF results in a facile SNAr reaction and N-arylation. The reaction is less satisfactory with pyridines unless an add
Towards aryl C-N bond formation in dynamic thin films
Gandy, Michael N.,Raston, Colin L.,Stubbs, Keith A.
supporting information, p. 4594 - 4597 (2014/06/24)
C-N bond forming reactions are important in organic chemistry. A thin film microfluidic vortex fluidic device (VFD) operating under confined mode affords N-aryl compounds from 2-chloropyrazine and the corresponding amine, without the need for a transition
