98943-13-6Relevant articles and documents
Synthesis of alkyl-substituted arecoline derivatives as γ-aminobutyric acid uptake inhibitors
Muller-Uri,Singer,Fleischhacker
, p. 125 - 132 (2007/10/02)
A series of N-methyltetrahydropyridine-3-carboxylic acids and methyl esters have been synthesized and biologically evaluated. Arecoline (6) was lithiated with LDA in THF to give 7, which was treated with various alkyl halides to afford exclusively the α-s