98944-82-2

Upstream product

• 542-05-2 acetonedicarboxylic acid 
• 5362-56-1 4-methylpent-2-enal 
• 23396-36-3 3-isopropylcyclohexanone 

Downstream Products

• 342794-03-0 (R)-5-isopropyl-cyclohex-2-enone 
• 342794-05-2 (S)-3-Ethyl-5-isopropyl-cyclohexanone 
• 1373048-99-7 (5R)-3-isopropyl-5-phenylcyclohexanone 
• 1373048-98-6 (3R,5R)-3-isopropyl-5-phenylcyclohexan-1-one 
• 1373048-87-3 (1R,5R)-5-isopropyl-1-methylcyclohex-2-en-1-ol 
• 1373048-93-1 (3S,5S)-3-isopropyl-5-phenylcyclohexan-1-one 
• 1373048-94-2 C₁₅H₂₀O 
• 1373048-90-8 C₉H₁₄O 

Relevant academic research and scientific papers

Soft Enolization of 3-Substituted Cycloalkanones Exhibits Significantly Improved Regiocontrol vs Hard Enolization Conditions

Soft enolization conditions are revealed to be markedly better than the typically applied hard enolization protocols for regioselective enoxysilane formation from unsymmetrical 3-substituted cycloalkanones. Five-, six-, and seven-membered cycloalkanones each with 3-methyl, 3-isopropyl, or 3-phenyl substituents were investigated, and in all but one case, regioselectivities were ≥11:1 for enolization away from the substituent. These results are complementary to the regiospecific enoxysilane formation derived from cycloalkenone conjugate addition/enolate silylation.

Synergistic Cu-amine catalysis for the enantioselective synthesis of chiral cyclohexenones

An unprecedented utilization of 1,3-acetonedicarboxylic acid as a 1,3-bis-pro-nucleophile and a reactive acetone surrogate in enantioselective catalysis has been reported. By synergistically activating the ketodiacid by copper catalysis and an α,β-unsatur