99026-77-4

Basic information

• Product Name: GLY-LYS-GLY-ALA-GLY-LEU-SER-LEU-SER-ARG-PHE-SER-TRP-GLY-ALA
• Synonyms: GLY-LYS-GLY-ALA-GLY-LEU-SER-LEU-SER-ARG-PHE-SER-TRP-GLY-ALA;[ALA107]-MBP (104-118);[ALA107]-MBP FRAGMENT 104-118;[ALA107]-MYELIN BASIC PROTEIN FRAGMENT 104-118;[Ala107]-Myelin Basic Protein (104-118)
• CAS NO: 99026-77-4
• Molecular Formula: C67H104N20O19
• Molecular Weight: 1493.67
• Product Categories: Protein Kinase
• Mol File: 99026-77-4.mol
• Article Data: 0

Chemical Properties

• Appearance: /
• Storage Temp.: −20°C
• Solubility: Soluble to 1 mg/ml in 10% acetonitrile
• CAS DataBase Reference: GLY-LYS-GLY-ALA-GLY-LEU-SER-LEU-SER-ARG-PHE-SER-TRP-GLY-ALA(CAS DataBase Reference)
• NIST Chemistry Reference: GLY-LYS-GLY-ALA-GLY-LEU-SER-LEU-SER-ARG-PHE-SER-TRP-GLY-ALA(99026-77-4)
• EPA Substance Registry System: GLY-LYS-GLY-ALA-GLY-LEU-SER-LEU-SER-ARG-PHE-SER-TRP-GLY-ALA(99026-77-4)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 99026-77-4(Hazardous Substances Data)

Usage

Biological Activity

[ala107]-mbp (104-118) is a non-competitive inhibitor of pkc and synthetic peptide analog of bovine myelin basic protein (mbp) with ic50 value of 46 - 145 mm.1. substrate specificity of phospholipid/ca2+ dependent protein kinase as probed with synthetic peptide fragments of the bovine myelin basic protein. turner et al. j.biol.chem., 1985;260:115032. synthetic myelin basic protein peptide analogs are specific inhibitors of phospholipid/calcium-dependent protein kinase (protein kinase c). su et al. biochem.biophys.res.commun., 1986;134:78

Biochem/physiol Actions

[Ala107]-Myelin Basic Protein Fragment 104-118 is an inhibitor of protein kinase C.