99059-64-0 Usage
Uses
3-Iodo-4-isopropylbenzoic Acid is used as a reactant in the preparation of novel ponatinib analogs as potent FGFRs inhibitors. It is a COVID19-related research product.
Check Digit Verification of cas no
The CAS Registry Mumber 99059-64-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,9,0,5 and 9 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 99059-64:
(7*9)+(6*9)+(5*0)+(4*5)+(3*9)+(2*6)+(1*4)=180
180 % 10 = 0
So 99059-64-0 is a valid CAS Registry Number.
InChI:InChI=1/C10H11IO2/c1-6(2)8-4-3-7(10(12)13)5-9(8)11/h3-6H,1-2H3,(H,12,13)
99059-64-0Relevant articles and documents
Novel Class of Colony-Stimulating Factor 1 Receptor Kinase Inhibitors Based on an o-Aminopyridyl Alkynyl Scaffold as Potential Treatment for Inflammatory Disorders
Xie, Zhicheng,Wu, Bing,Liu, Yingqiang,Ren, Wenming,Tong, Linjiang,Xiang, Caigui,Wei, Aihuan,Gao, Yuanzhuo,Zeng, Limin,Xie, Hua,Tang, Wei,Hu, Youhong
, p. 1397 - 1414 (2020/02/04)
Colony-stimulating factor 1 receptor (CSF-1R) is involved in inflammatory disorders as well as in many types of cancer. Based on high-throughput screening and docking results, we performed a detailed structure-activity-relationship study, leading to the d
