99067-39-7 Usage
Uses
Used in Organic Synthesis:
2-(dibromoMethyl)-5-nitrophenyl acetate is utilized as a reagent in various chemical reactions for its ability to participate in a wide array of organic synthesis processes. Its unique structure and reactivity make it a key component in creating new organic compounds.
Used in Pharmaceutical Preparation:
In the pharmaceutical industry, 2-(dibromoMethyl)-5-nitrophenyl acetate is used as an intermediate for the preparation of diverse pharmaceuticals. Its versatility in undergoing functionalization reactions allows for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Production:
2-(dibromoMethyl)-5-nitrophenyl acetate also finds application in the agrochemical sector, where it serves as an intermediate in the synthesis of various agrochemicals. Its role in creating effective compounds for agricultural use underscores its importance in this industry.
Used in Chemical Research:
In the realm of chemical research, 2-(dibromoMethyl)-5-nitrophenyl acetate is employed as a model compound to study the effects of functional groups on chemical reactivity and to explore new pathways in organic synthesis. Its unique properties make it an interesting subject for scientific investigation and potential innovation in chemical processes.
Check Digit Verification of cas no
The CAS Registry Mumber 99067-39-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,9,0,6 and 7 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 99067-39:
(7*9)+(6*9)+(5*0)+(4*6)+(3*7)+(2*3)+(1*9)=177
177 % 10 = 7
So 99067-39-7 is a valid CAS Registry Number.
99067-39-7Relevant academic research and scientific papers
Discovery of inhibitors of aberrant gene transcription from libraries ofdna binding molecules: Inhibition of LEF-1-mediated gene transcription and oncogenic transformation
Stover, James S.,Shi, Jin,Jin, Wei,Vogt, Peter K.,Boger, Dale L.
supporting information; experimental part, p. 3342 - 3348 (2009/07/30)
The screening of a >9000 compound library of synthetic DNA binding molecules for selective binding to the consensus sequence of the transcription factor LEF-1 followed by assessment of the candidate compounds in a series of assays that characterized functional activity (disruption of DNA-LEF-1 binding) at the intended target and site (inhibition of intracellular LEF-1-mediated gene transcription) resulting in a desired phenotypic cellular change (inhibit LEF-1-driven cell transformation) provided two lead compounds: lefmycin-1 and lefmycin-2. The sequence of screens defining the approach assures that activity in the final functional assay may be directly related to the inhibition of gene transcription and DNA binding properties of the identified molecules. Central to the implementation of this generalized approach to the discovery of DNA binding small molecule inhibitors of gene transcription was (1) the use of a technically nondemanding fluorescent intercalator displacement (FID) assay for initial assessment of the DNA binding affinity and selectivity of a library of compounds for any sequence of interest, and (2) the technology usedto prepare a sufficiently large library of DNA binding compounds.
