99068-23-2Relevant academic research and scientific papers
Tert -Butyl nitrite promoted transamidation of secondary amides under metal and catalyst free conditions
Sureshbabu, Popuri,Azeez, Sadaf,Chaudhary, Priyanka,Kandasamy, Jeyakumar
supporting information, p. 845 - 850 (2019/01/30)
A mild and efficient method is demonstrated for the transamidation of secondary amides with various amines including primary, secondary, cyclic and acyclic amines in the presence of tert-butyl nitrite. The reaction proceeds through the N-nitrosamide intermediate and provides the transamidation products in good to excellent yields at room temperature. Moreover, the developed methodology does not require any catalyst or additives.
Desulfurization of Thioamides into Amides with Dinitrogen Tetroxide
Kim, Hyung Jin,Kim, Yong Hae
, p. 970 - 972 (2007/10/02)
Secondary and tertiary thioamides or diphenylthionocarbonate reacted readily with dinitrogen tetroxide at ca. 0 deg C in acetonitrile to afford the corresponding amides or carbonate in good to excellent yields.The desulfurization appears to proceed via an S-nitroso intermediate by the selective electrophilic attack of nitrosonium cation on the thione sulfur atom.
