99107-70-7Relevant academic research and scientific papers
Thermal and photochemical reactions of Fischer carbene complexes with trialkylsilyl-substituted alkynes
Li, Zhi,Moser, William H.,Zhang, Wenqin,Hua, Changhua,Sun, Liangdong
, p. 361 - 367 (2008/03/14)
Thermal reaction of Fischer carbene complexes with triisopropylsilyl (TIPS) substituted alkynes in benzene afforded TIPS-substituted vinylketenes or 2-TIPS-substituted cyclobutenones as major products while photochemical reaction of Fischer carbene comple
A novel and highly regioselective Cr-mediated route to functionalised quinone boronic ester derivatives
Davies, Mark W.,Johnson, Christopher N.,Harrity, Joseph P. A.
, p. 2107 - 2108 (2007/10/03)
A novel and highly regioselective route to quinone boronic ester derivatives has been developed using a Fischer carbene mediated benzannulation process.
1,4-Dihydronaphthoquinones, hydroindoloquinones, benzofurans, and benzothiophenes as inhibitors of 5-lipoxygenase. Synthesis and structure-activity studies
Yamashita,Schaub,Back,White,Toy,Ghazal,Burdick,Brashler,Holm
, p. 775 - 781 (2007/10/02)
A series of substituted 1,4-dihydronaphthoquinones, hydroindoloquinones, benzofuran-4,7-dihydroquinones, and benzothiophene-4,7-dihydroquinones were synthesized and evaluated for inhibitory activity against 5-lipoxygenase. These compounds were found to be active in vitro for LTC4/D4 inhibition with the potencies (IC50's) ranging from 0.2 to 85 μM. Active 1,4-dihydronaphthoquinone acetates (IC50 4 inhibition assay. The acetates of 1,4-dihydronaphthoquinones containing the alkyl substituent(s) (2-n-butyl, 11, and 2,3-diethyl, 15) exhibited the best activity in LTC4/D4 inhibition (IC50 = 0.2-0.4 μM, in vitro) as well as in LTB4 inhibition (60-75% inhibition).
REACTION OF ARYL CHROMIUM CARBENE COMPLEXES WITH 1-HEXYNE; FORMATION OF UNUSUAL DIELS-ALDER CYCLOADDITION PRODUCTS
Yamashita, A.,Timko, J.M.,Watt, W.
, p. 2513 - 2516 (2007/10/02)
The reaction of an aryl chromium carbene complex with 1-hexyne provided a benzannualated product as a major component along with unusual Diels-Alder cycloaddition products.
