99117-21-2

Basic information

• Product Name: 2-BENZYL-1,2,3,4-TETRAHYDRO-BENZO[B][1,6]NAPHTHYRIDINE-10-CARBOXYLIC ACID
• Synonyms: 2-(benzyl)-3,4-dihydro-1H-pyrido[4,3-b]quinolin-2-ium-10-carboxylate;2-(benzyl)-3,4-dihydro-1H-pyrido[4,3-b]quinoline-10-carboxylic acid;2-(phenylmethyl)-3,4-dihydro-1H-pyrido[4,3-b]quinolin-2-ium-10-carboxylate;2-(phenylmethyl)-3,4-dihydro-1H-pyrido[4,3-b]quinoline-10-carboxylic acid
• CAS NO: 99117-21-2
• Molecular Formula: C₂₀H₁₈N₂O₂
• Molecular Weight: 318.38
• Mol File: 99117-21-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 504.4°Cat760mmHg
• Flash Point: 258.9°C
• Appearance: /
• Density: 1.296g/cm³
• Vapor Pressure: 5.37E-11mmHg at 25°C
• Refractive Index: 1.691
• CAS DataBase Reference: 2-BENZYL-1,2,3,4-TETRAHYDRO-BENZO[B][1,6]NAPHTHYRIDINE-10-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 2-BENZYL-1,2,3,4-TETRAHYDRO-BENZO[B][1,6]NAPHTHYRIDINE-10-CARBOXYLIC ACID(99117-21-2)
• EPA Substance Registry System: 2-BENZYL-1,2,3,4-TETRAHYDRO-BENZO[B][1,6]NAPHTHYRIDINE-10-CARBOXYLIC ACID(99117-21-2)

Safety Data

• Hazardous Substances Data: 99117-21-2(Hazardous Substances Data)

Usage

InChI:InChI=1/C20H18N2O2/c23-20(24)19-15-8-4-5-9-17(15)21-18-10-11-22(13-16(18)19)12-14-6-2-1-3-7-14/h1-9H,10-13H2,(H,23,24)

Upstream product

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Relevant articles and documents

COMPOSITIONS AND METHODS FOR TREATING MALARIA

Disclosed are methods of treating malaria with tetrahydrobenzonaphtyridine carboxanilide (TBN) derivatives and related pyrrolinones and hydrolysis products thereof. These compounds are active against Plasmodium falciparum strains that are resistant to multiple drugs currently on the market. The present invention further relates to novel compounds and pharmaceutical compositions comprising such compounds.