99177-33-0 Usage
Uses
Used in Organic Synthesis:
(4-bromo-benzyl)-isopropyl-amine; hydrochloride is used as a reagent for the synthesis of various organic compounds, leveraging its structural features and reactivity to facilitate the formation of desired products.
Used in Pharmaceutical Production:
In the pharmaceutical industry, (4-bromo-benzyl)-isopropyl-amine; hydrochloride serves as an intermediate in the production of various pharmaceuticals, contributing to the development of new drugs and medications.
Used in Chemical Research:
(4-bromo-benzyl)-isopropyl-amine; hydrochloride is also employed in chemical research as a tool to study and understand the properties and reactions of different chemical groups, such as benzyl, isopropyl, and amine groups, as well as their interactions with other molecules.
Used in Medicinal Chemistry and Drug Development:
Due to its structural features and reactivity, (4-bromo-benzyl)-isopropyl-amine; hydrochloride may have potential applications in medicinal chemistry and drug development, where it could be used to design and synthesize new therapeutic agents or improve the properties of existing drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 99177-33-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,9,1,7 and 7 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 99177-33:
(7*9)+(6*9)+(5*1)+(4*7)+(3*7)+(2*3)+(1*3)=180
180 % 10 = 0
So 99177-33-0 is a valid CAS Registry Number.
99177-33-0Relevant academic research and scientific papers
Towards the Development of Frustrated Lewis Pair (FLP) Catalyzed Hydrogenations of Tertiary and Secondary Carboxylic Amides
K?ring, Laura,Paradies, Jan,Sitte, Nikolai A.
, p. 1287 - 1300 (2022/01/20)
The development of the frustrated Lewis pair catalyzed hydrogenation of tertiary and secondary amides is reviewed. Detailed insight into our strategies in order to overcome challenges during the reaction development process is provided. Furthermore, the d
Hydrogenation of Secondary Amides using Phosphane Oxide and Frustrated Lewis Pair Catalysis
K?ring, Laura,Sitte, Nikolai A.,Bursch, Markus,Grimme, Stefan,Paradies, Jan
supporting information, p. 14179 - 14183 (2021/09/03)
The metal-free catalytic hydrogenation of secondary carboxylic acid amides is developed. The reduction is realized by two new catalytic reactions. First, the amide is converted into the imidoyl chloride by triphosgene (CO(OCCl3)2) using novel phosphorus(V) catalysts. Second, the in situ generated imidoyl chlorides are hydrogenated in high yields by an FLP-catalyst. Mechanistic and quantum mechanical calculations support an autoinduced catalytic cycle for the hydrogenation with chloride acting as unusual Lewis base for FLP-mediated H2-activation.
