99233-59-7

Upstream product

• 18247-78-4 2-oxo-N-(4-chlorophenyl)propanehydrazonoyl chloride 
• 31058-74-9 N.N'-Bis-<4-chlor-phenyl>-C-acetyl-formazan 

Relevant academic research and scientific papers

Lipoxygenase inhibitors, IV: Synthesis and cyclization reactions of open-chain N1-aryl-substituted amidrazones

α-Carbonyl carboxylic acid arylhydrazonochlorides obtained by Japp-Klingemann reaction are the starting substances for the synthesis of α-carbonyl carboxylic acid arylhydrazonoamides, -esters and -thioesters. The inhibiting activity of these compounds against 15- and 5-lipoxygenase is described. Reactions of derivatives of amidrazones with formaldehyde give triazole, triazoline and unexpected benzotriazepine derivatives.