99259-17-3

Upstream product

• 79-22-1 methyl chloroformate 
• 1738-80-3 L-serine benzyl ester p-toluenesulfonate hydrochoride 

Downstream Products

• 96854-28-3 (R)-<2-(Benzyloxycarbonyl)-2-<(methoxycarbonyl)amino>ethyl>triphenylphosphonium Iodide 
• 136978-23-9 (S)-N-(Methoxycarbonyl)-O-(p-toluenesulfonyl)serine 
• 99259-18-4 (R)-3-Iodo-2-<(methoxycarbonyl)amino>propanoic Acid Benzyl Ester 
• 136978-25-1 -2-(methoxycarbonyl)amino-4-phenyl-3-butenoic acid 
• 136220-97-8 (S)-2-<(Methoxycarbonyl)amino>-4-phenylbutanoic Acid 
• 148469-28-7 (R)-<2-Carboxy-2-<(methoxycarbonyl)amino>ethyl>triphenylphosphonium Chloride 
• 136978-32-0 (S)-N-(Methoxycarbonyl)-O-(p-toluenesulfonyl)serine Benzyl Ester 

Relevant academic research and scientific papers

Synthesis and absolute configuration of wybutine, the fluorescent minor base from phenylalanine transfer ribonucleic acids

The phosphonium chloride 6 having an optically active amino acid moiety was synthesized from (S)-serine benzyl ester tosylate (2b) through a six-step route. The utility of 6 as a reagent for the Wittig reaction was exemplified in the olefination with benz

SYNTHESIS OF (S)-(-)-WYBUTINE, THE FLUORESCENT MINOR BASE FROM YEAST PHENYLALANINE TRANSFER RIBONUCLEIC ACIDS

The Wittig reaction of 1-benzyl-7-formylwye (12) with (R)-ethyl>triphenylphosphonium chlorid (8) followed by successive methylation and reduction gave (-)-wybutine .