99268-41-4Relevant academic research and scientific papers
Structure of Obafluorin: An Antibacterial β-Lactone from Pseudomonas fluorescens
Tymiak, Adrienne A.,Culver, Catherine A.,Malley, Mary F.,Gougoutas, Jack Z.
, p. 5491 - 5495 (1985)
Fermentation of Pseudomonas fluorescens (ATCC 39502) produces obafluorin (1), a novel β-lactone antibiotic.Isolation and structure determination of obafluorin are described.The skeleton and relative stereochemistry of 1 were established by using nuclear magnetic resonance and mass spectrometric and X-ray crystallographic analyses.The absolute configuration was deduced from enzymatic degradation of an amino acid fragment produced by hydrolysis of 1.Structural and biological aspects of obafluorin are discussed.
