99274-45-0Relevant academic research and scientific papers
Synthesis of Substituted 3-(β,β-Dimethylhydrazino)-2-methoxy-2-oxo-1,2-oxaphospholanes
Wroblewski, Andrzej E.
, p. 407 - 415 (2007/10/02)
Cyclisation of δ-(N,N-dimethylhydrazono)alkyl phosphites afforded the title compounds in moderate to high yields.The ring closure was highly diastereoselective leading to an excess of the diastereomers with the β,β-dimethylhydrazino and MeOP groups in the trans configuration.The structure and relative configurations of diastereomeric pairs were established by 1H and 13C NMR spectroscopy.A mechanism of cyclisation was proposed. - Key words: 3-(β,β-Dimethylhydrazino)-1,2-oxaphospholanes, Diastereoselectivity, Configuration, Mechanism, Equilibration
