99300-05-7

Upstream product

• 34837-55-3 Phenylselenyl bromide 
• 1666-13-3 diphenyl diselenide 

Downstream Products

• 99285-03-7 Benzoic acid (2S,3S,4S,5S,6R,8R,9R,11R)-9-benzyloxy-2-ethyl-8-((S)-2-hydroxy-1-methyl-ethyl)-3-methoxymethoxy-3,5,9,11-tetramethyl-1,7-dioxa-spiro[5.5]undec-4-yl ester 
• 99285-00-4 (2R,3R,5R,6R,8S,9R,10S,11S)-2-[(S)-2-(tert-Butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-8-ethyl-9-methoxymethoxy-3,5,9,11-tetramethyl-1,7-dioxa-spiro[5.5]undecane-3,10-diol 
• 99285-04-8 Benzoic acid (2S,3S,4S,5S,6R,8R,9R,11R)-9-benzyloxy-2-ethyl-3-methoxymethoxy-3,5,9,11-tetramethyl-8-((R)-1-methyl-2-oxo-ethyl)-1,7-dioxa-spiro[5.5]undec-4-yl ester 
• 99285-05-9 Benzoic acid (2S,3S,4S,5S,6R,8R,9R,11R)-9-benzyloxy-2-ethyl-3-hydroxy-8-((1S,2S,3R)-2-hydroxy-3-methoxycarbonyl-1-methyl-butyl)-3,5,9,11-tetramethyl-1,7-dioxa-spiro[5.5]undec-4-yl ester 
• 99285-01-5 Benzoic acid (2S,3S,4S,5S,6R,8R,9R,11R)-8-[(S)-2-(tert-butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-2-ethyl-9-hydroxy-3-methoxymethoxy-3,5,9,11-tetramethyl-1,7-dioxa-spiro[5.5]undec-4-yl ester 
• 99285-02-6 Benzoic acid (2S,3S,4S,5S,6R,8R,9R,11R)-9-benzyloxy-8-[(S)-2-(tert-butyl-diphenyl-silanyloxy)-1-methyl-ethyl]-2-ethyl-3-methoxymethoxy-3,5,9,11-tetramethyl-1,7-dioxa-spiro[5.5]undec-4-yl ester 
• 99285-06-0 (2R,3S,4S)-4-((2R,3R,5R,6R,8S,9R,10S,11S)-3-Benzyloxy-8-ethyl-9,10-dihydroxy-3,5,9,11-tetramethyl-1,7-dioxa-spiro[5.5]undec-2-yl)-3-hydroxy-2-methyl-pentanoic acid methyl ester 
• 99482-72-1 Benzoic acid (2S,3S,4S,5S,6R,8R,9R,11R)-9-benzyloxy-2-ethyl-8-((1S,2S,3S)-2-hydroxy-3-methoxycarbonyl-1-methyl-butyl)-3-methoxymethoxy-3,5,9,11-tetramethyl-1,7-dioxa-spiro[5.5]undec-4-yl ester 
• 99482-72-1 Benzoic acid (2S,3S,4S,5S,6R,8R,9R,11R)-9-benzyloxy-2-ethyl-8-((1S,2S,3R)-2-hydroxy-3-methoxycarbonyl-1-methyl-butyl)-3-methoxymethoxy-3,5,9,11-tetramethyl-1,7-dioxa-spiro[5.5]undec-4-yl ester 

Relevant academic research and scientific papers

The addition of electophiles on ester enolates containing an oxygen in the β-position. A stereoelctronically controlled reaction

The enolate anion derived from spiro ketal methyl esters (1,3, and 4) reacts with various electrophiles (PhSeBr, CH3I, O2, I2, (CH3S)2, and (PhS)2 to yield as the major product, the isomer resulting from an equatorial approach of the electrophilic reagent.This stereochemically controlled reaction is discusseed in terms of stereoelectronic effects that increase the electron density of the α face of the enolate anion.