99333-59-2Relevant academic research and scientific papers
Triphosgene: A versatile reagent for the synthesis of azetidin-2-ones
Krishnaswamy,Govande,Gumaste,Bhawal,Deshmukh
, p. 2215 - 2225 (2007/10/03)
An efficient use of triphosgene, as an acid activator, for the synthesis of substituted azetidin-2-ones via ketene-imine cycloaddition reaction using various acids and imines have been described.
The asymmetric synthesis of β-lactam antibiotics. I. Application of chiral oxazolidones in the Staudinger Reaction
Evans,Sjogren
, p. 3783 - 3786 (2007/10/02)
The reactions of oxazolidone with N-benzylimines proceed with exceptional levels of asymmetric induction to form the cycloadducts. Subsequent dissolving metal reduction affords the homochiral β-lactam derivatives in good overall yield.
