99336-51-3

Upstream product

• 101130-69-2 3-carbomethoxy-2-dimethylsulfimido-5-toluidino-1,4-benzoquinone 
• 99336-43-3 3-methoxy-5-(p-toluidino)<2,1>benzisoxazole-4,7-quinone 
• 67-68-5 dimethyl sulfoxide 
• 2150-46-1 Methyl 2,5-dihydroxybenzoate 
• 101130-36-3 2,5-bis-p-toluidino-3-carbomethoxy-1,4-benzoquinone 

Downstream Products

• 99336-43-3 3-methoxy-5-(p-toluidino)<2,1>benzisoxazole-4,7-quinone 

Relevant academic research and scientific papers

Quninone Chemistry. Synthesis of 3-Methoxybenzisoxazole- and 3-Methoxynaphthisoxazolequinones

Benzisoxazole-4,7-quinones 4 are prepared by an improved method using oxidative amination of 1 to give 2, followed by amine exchange to 3 and cyclization with lead tetraacetate.Naphthisoxazole-4,9-quinone 7 is obtained from 5 by an analogous procedure.

Rearrangement of 3-Methoxy Substituted Benzisoxazole- and Naphthisoxazolequinones in Dimethyl Sulfoxide Solution

The reactions of the 3-methoxy-isoxazole quinones 1 and 9 in a highly polar solution of dimethyl sulfoxide have been studied.Quinones of type 2,4/11,5/12,6 and 7/13 have been isolated; nmr measurements give a detailed insight into the reaction mechanism.

Quninone Chemistry. Synthesis of 3-Dialkylsulfoximido- and 2-Dialkylsulfimido-3-carbomethoxy-1,4-benzo- and Naphthoquinone Derivatives

3-Methoxybenzisoxazole-4,7-quinones 1 and naphthisoxazole-4,9-quinone 4 react with dimethyl sulfoxides to give sulfoximidoquinones 2 and 5, sulfimidoquinones 8 and 11 respectively as major products.