99359-77-0

Upstream product

• 71-43-2 benzene 
• 515-40-2 neophyl chloride 

Downstream Products

• 83493-80-5 4-(2'-chloro-1',1'-dimethylethyl)ethoxybenzene 
• 1067192-73-7 3-methyl-3-(4-nitro-phenyl)-butyronitrile 
• 1067193-11-6 {3-[4-(3,4-dimethoxy-benzoylamino)-phenyl]-3-methyl-butyl}-carbamic acid tert-butyl ester 
• 1067191-56-3 N-(4-(4-acetamido-2-methylbutan-2-yl)phenyl)-3,4-dimethoxybenzamide 
• 1067193-12-7 N-[4-(3-amino-1,1-dimethyl-propyl)-phenyl]-3,4-dimethoxy-benzamide 
• 1067192-93-1 N-[3-methyl-3-(4-nitro-phenyl)-butyl]-acetamide 
• 1067192-96-4 N-(3-(4-aminophenyl)-3-methylbutyl)acetamide 
• 1067192-92-0 3-methyl-3-(4-nitro-phenyl)-butylamine 
• 80854-21-3 3-phenoxybenzyl 2-(4-hydroxyphenyl)-2-methylpropyl ether 
• 80844-07-1 etofenprox 

Relevant academic research and scientific papers

Synthesis of ethophenprox

An ethophenprox synthesis from easily available p-nitroneophyl chloride was developed. The reduction of the latter to aniline derivative followed by Sandmayer's and Claisen's reactions furnished p-ethoxyneophyl chloride that by condensation with 3-phenoxybenzyl alcohol in the presence KOH in DMSO yielded ethophenprox.

NOVEL BENZAMIDE DERIVATIVES AS MODULATORS OF THE FOLLICLE STIMULATING HORMONE

The present invention provides new compounds of formula I, wherein Q, R1, R2, R4, R5, R6, Xi, R7, R8, M and G1 nare defined as in formula I; invention compounds are modulators of follicle-stimulating hormone - ("FSH") which are useful for male and female contraception as well as other disorders modulated by FSH receptor.