99364-30-4

Upstream product

• 103-71-9 phenyl isocyanate 
• 96559-07-8 {(2S,3R)-3-[(S)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-2-[2-(tert-butyl-diphenyl-silanyloxy)-acetylsulfanyl]-4-oxo-azetidin-1-yl}-oxo-acetic acid allyl ester 
• 96593-74-7 (5R,6S)-6-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-3-(tert-butyl-diphenyl-silanyloxymethyl)-7-oxo-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid allyl ester 
• 86998-57-4 (tert-Butyl-diphenyl-silanyloxy)-thioacetic acid S-{(2S,3R)-3-[(S)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-oxo-azetidin-2-yl} ester 
• 88585-78-8 (5R,6S)-6-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-3-hydroxymethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid allyl ester 
• 99364-27-9 (5R,6S)-6-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-7-oxo-3-phenylcarbamoyloxymethyl-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid allyl ester 
• 99364-27-9 (5R,6S)-6-[(R)-1-(tert-Butyl-dimethyl-silanyloxy)-ethyl]-7-oxo-3-phenylcarbamoyloxymethyl-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid allyl ester 

Relevant academic research and scientific papers

2-(HETEROATOM-SUBSTITUTED)METHYL PENEMS. IV. OXYGEN DERIVATIVES

The synthesis of "2-CH2X" penems wherein X is an oxygen atom part of an acyloxy, N-substituted carbamoyloxy, alkoxy or aryloxy residue is described, with emphasis to procedures which exploit a common 2-hydroxymethylpenem precursor.Correlations are attempt

SYNTHESIS OF NEW PENEM DERIVATIVES: N-SUBSTITUTED ANALOGS OF FCE 22101

New penem derivatives, analogs of FCE 22101 with N-substitution at the carbamoyl moiety, have been synthesized by using a new catalytic action of 4-dimethylaminopyridine.