99366-56-0Relevant academic research and scientific papers
Enantioselective Synthesis of Arene cis-Dihydrodiols from 2-Pyrones
Liang, Xiao-Wei,Zhao, Yunlong,Si, Xu-Ge,Xu, Meng-Meng,Tan, Jia-Hao,Zhang, Zhi-Mao,Zheng, Cheng-Gong,Zheng, Chao,Cai, Quan
supporting information, p. 14562 - 14567 (2019/09/06)
An enantioselective chemical synthesis of arene cis-dihydrodiols has been realized from 2-pyrones through sequential ytterbium-catalyzed asymmetric inverse-electron-demand Diels–Alder (IEDDA) reaction of 2-pyrones and retro-Diels–Alder extrusion of CO2. By using this strategy, a series of substituted arene cis-dihydrodiols can be obtained efficiently with high enantioselectivity (>99 % ee in many cases). Based on this strategy, efficient and concise asymmetric total syntheses of (+)-MK7607 and 1-epi-(+)-MK7607 were accomplished.
Reaction de quelques pyrazolines substituees par deux groupes electroattracteurs gemines avec Ce(NH4)2(NO3)6: nouvelle synthese de pyrones-2 electrophiles
Abdallah, Hassan,Gree, Rene,Carrie, Robert
, p. 3031 - 3036 (2007/10/02)
Reaction of type 3 ketal pyrazolines with Ce(NH4)2(NO3)6 is studied.This leads generally to olefins 4, which are good starting materials for the synthesis of electrophilic pyrones 5.In two cases, another pathway leading to cyclobutanes is observed.
