99423-94-6

Upstream product

• 71924-61-3 3-fluoro-4,5-dimethoxybenzaldehyde 

Downstream Products

• 476359-35-0 (2R)-N-[(2S)-2-((diphenylmethylidene)amino)-2-(2',6'-difluoro-3',4'-dimethoxybenzyl)-ethan-1-oyl]bornane-10,2-sultam 
• 476359-33-8 (2R)-N-[(2S)-2-((diphenylmethylidene)amino)-2-(5'-fluoro-3',4'-dimethoxybenzyl)-ethan-1-oyl]bornane-10,2-sultam 
• 476359-39-4 (2R)-N-[(2S)-2-amino-2-(2',6'-difluoro-3',4'-dimethoxybenzyl)-ethan-1-oyl]bornane-10,2-sultam 
• 476359-37-2 (2R)-N-[(2S)-2-amino-2-(5'-fluoro-3',4'-dimethoxybenzyl)-ethan-1-oyl]bornane-10,2-sultam 
• 128812-04-4 2,6-difluoro-L-3,4-dihydroxyphenylalanine 
• 476359-43-0 2,6-difluoro-L-3,4-dimethoxyphenylalanine 
• 476359-41-8 5-fluoro-L-3,4-dimethoxyphenylalanine 
• 476359-31-6 2-chloromethyl-1,3-difluoro-4,5-dimethoxy-benzene 
• 102034-50-4 1-fluoro-2,3-dimethoxy-5-chloromethylbenzene 

Relevant academic research and scientific papers

Convenient syntheses of 2-, 5- and 6-fluoro- and 2,6-difluoro-L-DOPA

Alkylation under phase transfer conditions of the chiral glycine synthon 2 (prepared from the commercially available Oppolzer chiral sultam) with fluorinated analogues of 3,4-dimethoxybenzyl chloride proceeded with high diastereoselectivity. Hydrolysis of