99440-31-0

Upstream product

• 41641-14-9 1-hydroxymethyl-3,3-dimethyl-cyclohex-1-ene 
• 78-39-7 Triethyl orthoacetate 
• 67218-06-8 6-(butylsulfanyl-methylene)-2,2-dimethyl-cyclohexanone 
• 1193-18-6 3-methylcyclohexen-2-one 
• 178616-56-3 6-[1-Butylsulfanyl-meth-(Z)-ylidene]-2,2-dimethyl-cyclohexanol 
• 76337-18-3 3,3-Dimethylcyclohex-1-ene-1-carbaldehyde 

Downstream Products

• 105426-83-3 2-(2',2'-dimethyl-6'-methylenecyclohexyl)1-(3-furyl)ethanone 
• 547-15-9 2-(6',6'-Dimethyl-2'-methylenecyclohexyl)ethanal 
• 331822-09-4 2-(6,6-Dimethyl-2-methylenecyclohexyl)ethyl methanesulfonate 
• 163041-14-3 Methyl 2,3-dihydro-2-methyl-2-[2-(2,2-dimethyl-6-methylenecyclohexyl)ethyl]-4-oxo-4H-1-benzopyran-3-carboxylate 
• 178616-59-6 (+/-)-2-(2-Iodoethyl)-3-methylene-1,1-dimethylcyclohexane 
• 84078-59-1 2-(2'-Methylene-6',6'-dimethylcyclohexyl)ethanol 
• 178616-52-9 Toluene-4-sulfonic acid 2-[2-(2-hydroxy-2,6,6-trimethyl-cyclohexyl)-ethyl]-3-oxo-butyl ester 
• 178616-51-8 3-Hydroxymethyl-5-(2-hydroxy-2,6,6-trimethyl-cyclohexyl)-pentan-2-one 
• 145631-62-5 5-((1R,2S)-2-Hydroxy-2,6,6-trimethyl-cyclohexyl)-3-methylene-pentan-2-one 
• 145631-62-5 5-((1R,2R)-2-Hydroxy-2,6,6-trimethyl-cyclohexyl)-3-methylene-pentan-2-one 
• 178616-50-7 2-[2-(2-Hydroxy-2,6,6-trimethyl-cyclohexyl)-ethyl]-butane-1,3-diol 
• 178616-60-9 (2R*S*,1'R*)-Methyl 2-<2-(6-methylene-2,2-dimethylcyclohexyl)ethyl>-3-oxobutanoate 
• 88214-43-1 1-<2'-(p-Toluenesulfonyl)ethyl>-2-methylene-6,6-dimethylcyclohexane 

Relevant academic research and scientific papers

A conjugate addition-radical cyclisation approach to sesquiterpene-phenol natural products

A conjugate addition-radical cyclization approach to sesquiterpenephenol natural products was discussed. The first step involved the conjugate addition of an organocopper species to a chromone-3-carboxylate which resulted in 2,2-disubstituted chroman-4-ones. The second step was the generation of a β-ketoester radical. The last step involved a stereoselective manganese(III) acetate-mediated radical cyclization reaction.

Synthesis of mono- and sesquiterpenoids, XXV: Synthesis of (6R*,7R*)-7-hydroxy-6,11-cyclofarnes-3(15)-en-2-one, the racemate of the antibacterial sesquiterpene from premna oligotricha, and its (6R*,7R*) isomer

The structure of the antibacterial sesquiterpene from Premna oligotricha was shown to be not 1 but 2 (relative stereochemistry) by the unambiguous synthesis of both (±)-1 and (±)-2. VCH Verlagsgesellschaft mbH, 1996.

A simple synthesis of γ-cyclohomocitral

A simple and efficient synthesis for γ-cyclohomocitral (10), a key and versatile intermediate for the synthesis of some furanosesquiterpenes, is described. The formal total synthesis of (±) Pallenscensone (2) was accomplished.