99441-22-2Relevant academic research and scientific papers
ABSOLUTE CONFIGURATION OF PARA- AND META-SUBSTITUTED 1-ARYL-1-ETHANOLS AND THEIR ACID PHTHALATES
Potapov, V. M.,Dem'yanovich, V. M.,Khlebnikov, V. A.
, p. 738 - 740 (2007/10/02)
The configuration of 1-aryl-1-ethanols and their acid phthalates can be established during the kinetic resolution of 1-aryl-1-ethanols in acylation by the action of phthalic anhydride in the presence of (S)-(-)-dimethyl(1-phenylethyl)amine.
Vibrational Circular Dichroism of Phenylcarbinols. A Configurational Correlation
Polavarapu, Prasad L.,Fontana, Luca P.,Smith, Howard E.
, p. 94 - 99 (2007/10/02)
The vibrational circular dichroism (VCD) spectra of enantiomers of phenylcarbaniols were studied in the 1600-800 cm-1 region.In these molecules, the PhC(OH)H group is a common structural feature, and the chirality of this probe group correlates with the sign of a VCD band at about 1200 cm-1.Viewing the probe group with the fourth ligand behind it, a clockwise arrangement of the probe group substituents (with the usual sequence rule priority, OH > Ph > H), designated as a clockwise probe group chirality, results in a negative sign for the VCD band at about 1200 cm-1.For a counterclockwise probe group chirality, the VCD band is positive.On the basis of infrared and Raman spectral observations with deuterated analogues, this band is assigned to a *C-H deformation mode of the phenylcarbinols.
