99448-74-5

Basic information

• Product Name: 1H-Indole-2,3-dione, 1-[(4-methylphenyl)sulfonyl]-
• CAS NO: 99448-74-5
• Molecular Formula: C15H11NO4S
• Molecular Weight: 301.323
• Mol File: 99448-74-5.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1H-Indole-2,3-dione, 1-[(4-methylphenyl)sulfonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-2,3-dione, 1-[(4-methylphenyl)sulfonyl]-(99448-74-5)
• EPA Substance Registry System: 1H-Indole-2,3-dione, 1-[(4-methylphenyl)sulfonyl]-(99448-74-5)

Safety Data

• Hazardous Substances Data: 99448-74-5(Hazardous Substances Data)

Upstream product

• 91-56-5 indole-2,3-dione 
• 98-59-9 p-toluenesulfonyl chloride 
• 50899-59-7 N-Hydroxymethylisatin 
• 3486-31-5 isatin sodium salt 

Downstream Products

• 110829-34-0 Z-3-thiosemicarbazone of 1-tosylisatin 
• 110829-35-1 thiosemicarbazide of N-tosylisatinic acid 
• 1173926-09-4 1′-tosyl-[3,3′:3′,3″-terindolin]-2′-one 
• 1173926-10-7 C₃₃H₂₇N₃O₃S 
• 1173926-11-8 C₃₃H₂₇N₃O₃S 
• 1178982-21-2 (R)-3-allyl-3-hydroxy-1-tosylindolin-2-one 
• 919787-30-7 3-diazo-1-tosylindolin-2-one 
• 31271-90-6 1-(p-toluenesulfonyl)-1H-indole 
• 39830-55-2 1-[(4-methylphenyl)sulfonyl]indoline 
• 22394-27-0 1-(p-toluenesulfonyloxy)-3-oxo-2,3-dihydroindole 

Relevant articles and documents

B(C6F5)3-Catalyzed Highly Chemoselective Reduction of Isatins: Synthesis of Indolin-3-ones and Indolines

A chemo- and site-selective reduction reaction of isatin derivatives using catalyst B(C6F5)3 and hydrosilanes is described. This transformation is operationally simple, proceeds under mild conditions, and is resistant to various functional groups. Thus, this efficient reaction using a combination of B(C6F5)3 and BnMe2SiH or B(C6F5)3 and Et2SiH2 could potentially be utilized to produce various indolin-3-ones and indolines, without the need for multistep procedures and metal catalysis conditions.

Features of interaction of 1-hydroxymethylisatin with certain P-, S-, and C-electrophiles

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