99474-06-3Relevant academic research and scientific papers
Synthesis of "Chiral" α-Aminoisobutyric Acid
Weihrauch, Thomas,Leibfritz, Dieter
, p. 1917 - 1921 (2007/10/02)
α-Methylalanine (α-aminoisobutyric acid), a rare naturally occuring achiral amino acid, is an efficient inducer of secondary structure for peptides and easy to characterize by NMR because of its prochiral methyl groups. "Chiral" α-methylalanine is enantioselectively synthesized via the bislactim-ether method where the pro-R-methyl group has three or one deuterium atom(s).
