99512-10-4

Basic information

• Product Name: Benzonitrile, 3-amino-4-nitro-
• Synonyms: Benzonitrile, 3-amino-4-nitro-;3-amino-4-nitrobenzonitrile
• CAS NO: 99512-10-4
• Molecular Formula: C₇H₅N₃O₂
• Molecular Weight: 163.14
• Mol File: 99512-10-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: Benzonitrile, 3-amino-4-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzonitrile, 3-amino-4-nitro-(99512-10-4)
• EPA Substance Registry System: Benzonitrile, 3-amino-4-nitro-(99512-10-4)

Safety Data

• RIDADR: 3439
• HazardClass: 6.1
• PackingGroup: Ⅲ
• Hazardous Substances Data: 99512-10-4(Hazardous Substances Data)

Usage

General Description

Benzonitrile, 3-amino-4-nitro- is a chemical compound with the molecular formula C7H5N3O2. It is commonly used in organic synthesis and as an intermediate in the production of pharmaceuticals, dyes, and agrochemicals. The compound is a yellow crystalline solid with a melting point of 82-84°C and a boiling point of 302-304°C. It is considered to be a hazardous substance and should be handled with care due to its potential for causing irritation to the skin, eyes, and respiratory system. Benzoinitrile, 3-amino-4-nitro- is also known to be toxic to aquatic organisms and may cause long-term adverse effects in the environment.

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Downstream Products

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Relevant articles and documents

INHIBITORS OF HISTONE DEACETYLASE

The invention relates to the inhibition of histone deacetylase. The invention provides compounds and methods for inhibiting histone deacetylase enzymatic activity. The invention also provides compositions and methods for treating cell proliferative diseases and conditions.

Nitroanilines are the reduction products of benzofuroxan system by oxyhemoglobin (HbO22+)

Benzofuroxans are interesting compounds which display several biochemical and pharmacological properties. Recent studies from our laboratory demonstrate that they are reduced by ferrous salts at room temperature and that the principal reaction products are o-nitroanilines. This paper shows that simple benzofuroxan derivatives are also able to oxidise HbO22+ to methemoglobin (MetHb3+) (UV detection) and to form o-nitroanilines (HPLC detection). From a toxicological point of view this reaction is interesting, since it indicates that the blood is a site for metabolism of these compounds with consequent methemoglobinemia and formation of toxic compounds.