99541-40-9

Basic information

• Product Name: 6-(phenylcarbonyl)-3-(piperidin-1-ylmethyl)-1,3-benzoxazol-2(3H)-one
• CAS NO: 99541-40-9
• Molecular Formula: C₂₀H₂₀N₂O₃
• Molecular Weight: 336.3844
• Mol File: 99541-40-9.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 502.1°C at 760 mmHg
• Flash Point: 257.5°C
• Density: 1.262g/cm³
• Vapor Pressure: 3.28E-10mmHg at 25°C
• Refractive Index: 1.62
• CAS DataBase Reference: 6-(phenylcarbonyl)-3-(piperidin-1-ylmethyl)-1,3-benzoxazol-2(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-(phenylcarbonyl)-3-(piperidin-1-ylmethyl)-1,3-benzoxazol-2(3H)-one(99541-40-9)
• EPA Substance Registry System: 6-(phenylcarbonyl)-3-(piperidin-1-ylmethyl)-1,3-benzoxazol-2(3H)-one(99541-40-9)

Safety Data

• Hazardous Substances Data: 99541-40-9(Hazardous Substances Data)

Upstream product

• 110-89-4 piperidine 
• 54903-12-7 6-benzoyl-2(3H)-benzoxazolone 
• 50-00-0 formaldehyd 

Relevant articles and documents

Analgesic and antiinflammatory activity screening of 6-acyl-3-piperidinomethyl-2(3H)-benzoxazolone derivatives

6-Acyl-2(3H)-benzoxazolone derivatives were reacted with appropriate piperidine derivatives and formaldehyde in methanol to give the corresponding 6-acyl-3-piperidinomethyl-2(3H)-benzoxazolones. The obtained compounds were screened for their analgesic and antiinflammatory activities. Analgesic activity of these compounds was investigated by modified Koster test. Antiinflammatory activity was assayed by using carrageenan induced mouse paw edema test and arachidonic acid edema. The 15 compounds synthesized showed good analgesic activities; compounds 1, 3 and 6 moved to be active inhibitors of edema.