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A-18-F-NH2, also known as 18F-labeled 5-(2-aminoethoxy)-N-(3-fluoropropyl)benzamide, is a radiolabeled chemical used in positron emission tomography (PET) imaging. It is a radiotracer that specifically binds to the sigma-1 receptor, a protein implicated in various neuropsychiatric disorders. A-18-F-NH2 has demonstrated potential in preclinical studies for visualizing the distribution and density of neuroreceptors in the brain, thereby aiding in the understanding and development of diagnostic and therapeutic strategies for conditions such as Alzheimer's disease, schizophrenia, and depression.

99588-52-0

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99588-52-0 Usage

Uses

Used in Neurology and Psychiatry:
A-18-F-NH2 is used as a PET imaging agent for visualizing the distribution and density of sigma-1 receptors in the brain. This application is crucial for understanding the role of these receptors in neuropsychiatric disorders such as Alzheimer's disease, schizophrenia, and depression.
Used in Diagnostic Imaging:
A-18-F-NH2 is used as a diagnostic tool to assess the involvement of sigma-1 receptors in the pathophysiology of neuropsychiatric disorders. Its ability to bind specifically to these receptors allows for the detection of changes in receptor density and distribution, which can provide valuable insights into disease progression and treatment response.
Used in Drug Development:
A-18-F-NH2 is used as a research tool in the development of new therapeutic strategies targeting sigma-1 receptors. By visualizing the interaction between A-18-F-NH2 and sigma-1 receptors, researchers can gain a better understanding of the receptor's role in neuropsychiatric disorders and identify potential drug candidates that modulate receptor activity.
Used in Preclinical Research:
A-18-F-NH2 is used as a radiotracer in preclinical studies to evaluate the potential of sigma-1 receptor-targeted therapies. These studies can provide valuable information on the efficacy, safety, and mechanism of action of new drugs, helping to guide their development and optimization for clinical use.

Check Digit Verification of cas no

The CAS Registry Mumber 99588-52-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,9,5,8 and 8 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 99588-52:
(7*9)+(6*9)+(5*5)+(4*8)+(3*8)+(2*5)+(1*2)=210
210 % 10 = 0
So 99588-52-0 is a valid CAS Registry Number.

99588-52-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name H-Ala-Gly-Glu-Gly-Leu-Ser-Ser-Pro-Phe-Trp-Ser-Leu-Ala-Ala-Pro-Gln-Arg-Phe-NH2

1.2 Other means of identification

Product number -
Other names A18Famide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:99588-52-0 SDS

99588-52-0Upstream product

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