99595-55-8Relevant academic research and scientific papers
Synthesis of 3,6-diaminophthalimides for ureidophthalimide-based foldamers
Sinkeldam, Renatus W.,Van Houtem, Michel H. C. J.,Koeckelberghs, Guy,Vekemans, Jef A. J. M.,Meijer
, p. 383 - 385 (2007/10/03)
Herein, we report an improved methodology for the synthesis of a variety of 3,6-diaminophthalimides in high yields. This enables decoration of the periphery of foldamers with a wide range of functionalities.
Synthesis and anti-tumor activity of nitrogen substituted thalidomide analogs
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, (2008/06/13)
The present invention comprises a group of compounds that effectively inhibit angiogenesis. More specifically, nitrogen-substituted thalidomide analogs and di-substituted thalidomide analogs have been shown to inhibit angiogenesis. Importantly, these compounds can be administered orally.
